Publications and Links





Donika Ivanova, Zhivko Zhelev, Plamen Getsov, Biliana Nikolova, Ichio Aoki, Tatsuya Higashi and Rumiana Bakalova, Vitamin K: Redox-modulation, prevention of mitochondrial dysfunction and anticancer effect. Redox Biol. 2018 Jun;16:352-358. doi: 10.1016/j.redox.2018.03.013. Epub 2018 Mar 20.

Donika Ivanova, Zhivko Zhelev, Dessislava Lazarova, Plamen Getsov, Rumiana Bakalova and Ichio Aoki, Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib. Anticancer Res. 2018 Mar;38(3):1407-1414.

Yousif Rojeab, Mohamad Hassoun, Ellen Hazelet and Deirdre Myers, HPLC Method Development and Validation for Simultaneous Quantification of Vitamins C and K3 in Hard Gelatin Capsules for their Potential Benefit in Postoperative Total Joint Arthroplasty, Annals of Clinical Research and Trials, V1, I2, 006

Xiaoyuan Ren, Thioredoxin and Glutaredoxin Systems under Oxidative and Nitrosative Stress, Thesis for doctoral degree (Ph.D.), 2017, Karolinska Institute, Stockholm, Sweden

Christophe Glorieux, JuanMarcelo Sandoval, Nicolas Dejeans, Geneviève Ameye, Hélène Antoine Poirel, Julien Verrax, Pedro Buc Calderon. Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones, Life Sciences 145 (2016) 57–65

Gilloteaux J, Ruffo C, Jamison JM, Summers JL. Modes of internalizations of human prostate carcinoma (DU145) cells in vitro and in murine xenotransplants. Ultrastruct Pathol. 2016 Sep-Oct;40(5):231-9. doi: 10.1080/01913123.2016.1174908. Epub 2016 May 10

Jacques Gilloteaux, Lee Laua, Ioulia Gouraria, DeborahNeal, James M.Jamison, J.L.Summers, Apatone® Induces Endometrioid Ovarian Carcinoma (MDAH 2774) Cells To Undergo Karyolysis And Cell Death By Autoschizis: A Potent And Safe Anticancer Treatment, Translational Research in Anatomy Volume 1, December 2015, Pages 25-39

Vânia Cristina Desoti, Danielle Lazarin-Bidóia, Fabianne Martins Ribeiro, Solange Cardoso Martins, Jean Henrique da Silva Rodrigues, Tania Ueda-Nakamura, Celso Vataru Nakamura, Valdecir Farias Ximenes, Sueli de Oliveira Silva, The Combination of Vitamin K3 and Vitamin C Has Synergic Activity against Forms of Trypanosoma cruzi through a Redox Imbalance Process, 2015

Gaston Silveira-Dorta, Diego M. Monzon, Fernando P. Crisostomo, Tomas Martın, Vıctor S. Martına and Romen Carrillo, Oxidation With Air By Ascorbate-Driven Quinone Redox Cycling, Chem. Commun., 2015, 51, 7027

J. Gilloteaux, J.M. Jamison, J.L. Summers, Autoschizis: a cell death induced by the anticancer, pro-oxidant stress of ascorbate:menadione combination,, July 2014

Jacques Gilloteaux, James M. Jamison, Deborah Neal, and Jack L. Summers, Synergistic Antitumor Cytotoxic Actions of Ascorbate and Menadione on Human Prostate (DU145) Cancer Cells In Vitro: Nucleus and Other Injuries Preceding Cell Death by Autoschizis Ultrastruct Pathol. 2014 Apr;38(2):116-40. doi: 10.3109/01913123.2013.852645. Epub 2014 Jan 24.

Gilloteaux Jacques, Jamison James M., Taper Henryk S., and Summers Jack L., The Antitumor Activity of Apatone® Against Human Prostate Cancer Correlates With Its Ability To Reactivate DNases And Induce Autoschizis, Journal of Men's Health. November 2013, 6(3): 248-248.

McGuire K, Jamison J, Gilloteaux J, Summers JL (2013) Vitamin C and K3 Combination Causes Enhanced Anticancer Activity against RT-4 Bladder Cancer Cells. J Cancer Sci Ther 5:325-333. doi:10.4172/1948-5956.1000223

McGuire K, Jamison J, Gilloteaux J, Summers JL (2013) Synergistic Antitumor Activity of Vitamins C and K3 on Human Bladder Cancer Cell Lines, Journal of Cancer Therapy, 2013, 4, 7-19

Jacques Gilloteaux, James M. Jamison, Jack L. Summers, Pro-oxidant Treatment of Human Prostate Carcinoma (DU145) Induces Autoschizis Cell Death: Autophagosomes Build up out of Injured Endomembranes and Mitochondria Ultrastruct Pathol. 2014 Oct;38(5):315-28. doi: 10.3109/01913123.2014.927404. Epub 2014 Jun 23.

Jacques Gilloteaux, James M. Jamison, Neal, David Arnold, Henryk S. Taper, and Jack l. Summers, Human Prostate DU145 Carcinoma Cells Implanted in Nude Mice Remove the Peritoneal Mesothelium to Invade and Grow as Carcinomas, The Anatomical Record 296:40–55 (2013)

McGuire, K., Jamison, J., Gilloteaux J., Summers, J. Synergistic Antitumor Activity of Vitamins C and K3 on Human Bladder Cancer Cell Lines Journal of Cancer Therapy, 2013, 4, 7-19 doi:10.4236/jct.2013.46A3002 Published Online February 2013 (

Tatyana V. Masyuk, Brynn N. Radtke, Angela J. Stroope, Jesús M. Banales, Anatoliy I. Masyuk, Sergio A. Gradilone, Gabriella Bedekovicsne Gajdos, Natasha Chandok, Jason L. Bakeberg, Christopher J. Ward, Erik L. Ritman, Hiroaki Kiyokawa, And Nicholas F. Larusso, Inhibition of Cdc25A Suppresses Hepato-renal Cystogenesis in Rodent Models of Polycystic Kidney and Liver Disease,  Gastroenterology 2012;142:622–633

Jacques Gilloteaux, James M. Jamison, Deborah R. Neal, Jack L. Summers, and Henryk S. Taper, Xenotransplanted Human Prostate Carcinoma (DU145) Cells Develop into Carcinomas and Cribriform Carcinomas: Ultrastructural Aspects,  Ultrastructural Pathology, 36(5), 294–311, 2012

Karen M. McGuire; Characterization Of Apatone And KST201 Induced Cell Death Mechanisms Against Bladder And Ovarian Cancer A dissertation submitted to Kent State University 2012

Imran Tadwee, Dr.Sadhana Shahi, Vivek Ramteke, Iftequar Syed, Liquid Crystals Pharmaceutical Application: A Review,    International Journal of Pharmaceutical Research & Allied SciencesVolume 1, issue2 (2012), 06-11

Raphael Beck, Nicolas Dejeans, Christophe Glorieux, Melanie Creton, Edouard Delaive, Marc Dieu, Martine Raes, Philippe Leveque, Bernard Gallez, Matthieu Depuydt, Jean-Francois Collet, Pedro Buc Calderon, Julien Verrax, Hsp90 Is Cleaved by Reactive Oxygen Species at a Highly Conserved N-Terminal Amino Acid Motif, PLoS ONE July 2012, Volume 7, Issue 7, e40795

Gilloteaux, J, Jamison, J., Meal, D., Summers, J.L., and Taper, H., Xenotransplanted Human Prostate Carcinoma (DU145) Cells Develop into Carcinomas and Cribriform Carcinomas: Ultrastructural Aspects, Ultrastructural Pathology,Oct 2012, 36(5), pg. 294–311.

Karen McGuire, Deborah Neal, Gail C. Fraizer, Jacques Gilloteaux, Henryk Taper and James Jamison, Oxidative stress induced by sodium ascorbate:menadione sodium-bisulfate combination results in lysosomal and mitochondrial changes that lead to prostate cancer cell death. Molecular and Cellular Biology, AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL

Christophe Glorieux, Nicolas Dejeans, Brice Sid, Raphael Beck, Pedro Buc Calderon, Julien Verrax, Catalase Overexpression In Mammary Cancer Cells Leads To A Less Aggressive Phenotype And An Altered Response To Chemotherapy, Biochemical Pharmacology 82 (2011) 1384–1390

Julien Verrax, Raphael Beck, Nicolas Dejeans, Christophe Glorieux, Brice Sida, Rozangel C. Pedrosa, Julio Benites, David Vásquez, Jaime A. Valderrama, and Pedro Buc Calderon,  Redox-Active Quinones and Ascorbate: An Innovative Cancer Therapy That Exploits the Vulnerability of Cancer Cells to Oxidative Stress,  Anticancer Agents Med Chem. 2011 Feb;11(2):213-21.

Julien Verrax, Nicolas Dejeans, Brice Sid, Christophe Glorieux, Pedro Buc Calderon, Intracellular ATP Levels Determine Cell Death Fate Of Cancer Cells Exposed To Both Standard And Redox Chemotherapeutic Agents, Biochemical Pharmacology 82 (2011) 1540–1548

Angelica R Bonilla-Porras, Marlene Jimenez-Del-Rio and Carlos Velez-Pardo, Vitamin K3 And Vitamin C Alone Or In Combination Induced Apoptosis In Leukemia Cells By A Similar Oxidative Stress Signaling Mechanism,  Cancer Cell Int. 2011; 11: 19.

Beck, R., Pedrosa, R., Dejeans, N., Glorieux, C., Leveque, P., Gallaz, B., Taper, H., et. Al., Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of oncogenic protein Bcr-Abl. An in vito and in vivo mechanistic study, Invest. New Drugs, 2011, 29(5), pg. 891 – 900.

Jamison,, J, Gillliteaux, J, Perlaky, L, Thiry, M, Smetana, K, Neal, D, McGuire, K, and Summers, J, Nucleolar Changes and Fibrillarin Redistribution Following Apatone Treatment of Human Bladder Carcinoma Cells, Journal of Histochemistry & Cytochemistry, Jul 2010, 58(7), pg. 635 – 651.

Gilloteaux, J, Jamison, J, Neal, D, Loukas,M, Doberzstyn,T, Summers, J, Cell Damage And Death By Autoschizis In Human Bladder (RT4) Carcinoma Cells Resulting From Treatment With Ascorbate And Menadione., Ultrastructure Pathology, 2010, 34, 140 – 160.

Vita MF, Nagachar N, Avramidis D, Delwar ZM, Cruz MH, Siden Å, Paulsson KM, Yakisich JS. Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C. Invest New Drugs. 2011 Dec;29(6):1314-20. doi: 10.1007/s10637-010-9489-0. Epub 2010 Jul 13.

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Caroline Diepart, Julien Verrax, Pedro Buc Calderon, Olivier Feron, Bénédicte F. Jordan, Bernard Gallez, Comparison Of Methods For Measuring Oxygen Consumption In Tumor Cells In Vitro. Anal Biochem. 2010 Jan 15;396(2):250-6. doi: 10.1016/j.ab.2009.09.029. Epub 2009 Sep 18.

Neal, D., McGuire, K., Shah,P., Kovacik, M., Mostardi, R., Walker, J., Ramsier, R., and Jamison, J., Apatone® Treatment Inhibits the Inflammatory Response in Human Synovial Fibroblasts Following Metal Particulate Exposure by Reducing NF-κB Levels, Proceedings of Microscopy and Microanalysis, 2009, pg 894.

Raphael Beck, Julien Verrax, Thomas Gonze, Marianne Zappone, Rozangela Curi Pedrosa, Henryk Taper, Olivier Feron, Pedro Buc Calderon, Hsp90 Cleavage By An Oxidative Stress Leads To Its Client Proteins Degradation And Cancer Cell Death, Biochemical Pharmacology 77 (2009) 375–383

Raphael Beck, Julien Verrax, Nicolas Dejeans, Henryk Taper, and Pedro Buc Calderon, Menadione Reduction by Pharmacological Doses of Ascorbate Induces an Oxidative Stress That Kills Breast Cancer Cells, International Journal of Toxicology Volume 28 Number 1 January/February 2009 33-42

Verrax J, Taper H, Buc Calderon P. Targeting Cancer Cells by an Oxidant-Based Therapy, Curr Mol Pharmacol. 2008 Jan;1(1):80-92.

McGuire, K., Jamison, J., Neal, D., Gilloteaux, J., and Summers, J.L., Elucidating the Pathway of Apatone® Induced DNase II Reactivation During Autoschizic Cell Death, Proceedings of Microscopy and Microanalysis, 2009, pg 888 – 889.

Taper HS, Altered Deoxyribonuclease Activity In Cancer Cells And Its Role In Non Toxic Adjuvant Cancer Therapy With Mixed Vitamins C And K3.  Anticancer Res. 2008 Sep-Oct;28(5A):2727-32.

Kovacik, M, Mostardi, R, Neal, D, Bear, T, Askew, M, Differences In The Surface Composition Of Seemingly Similar F75 Cobalt-Chromium Micron-Sized Particulates Can Affect Synovial Fibroblast Viability, Colloids And Surfaces B: Biointerfaces, 2008, 65, pg. 269 – 275.

Tareen, Basir, Summers, Jack L., Jamison, James M. J, Neal, Deborah R., McGuire, Karen,Gerson, Lowell ,Diokno, Ananias, A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy, Int J Med Sci , 2008, Mar 24,5(2), pg.62-67.

Verrax, J., Vanbever, S., Stocks, J., Taper, H., and Buc Calderson, P., Role Of Glycolysis Inhibition And Poly(ADP-Ribose) Polymerase Activation In Necrotic-Like Cell Death Caused By Ascorbate/Menadione Induced Oxidative Stress In K562 Human Chronic Myelogenous Leukemia Cells, Int J. of Cancer, 2007.

Kassouf, W., Highshaw, R., Nelkin, G., Dinney, C., and Kamatt, A., Vitamins C and K3 Sensitize Human Urothelial Tumors to Gemcitabine,The Journal of urology, 2006, 176, pg. 1642 – 1647.

Julien Verrax, Julie Stockis, Aurelie Tison, Henryk S. Taper, Pedro Buc Calderon, Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice. Biochemical Pharmacology 72 (2006) 67 1–680

Gilloteaux Jacques; Jamison James M; Arnold David; Neal Deborah R; Summers Jack L Morphology And DNA Degeneration During Autoschizic Cell Death In Bladder Carcinoma T24 Cells Induced By Ascorbate And Menadione Treatment. The Anatomical Record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2006;288A(1):58-83.

Gilloteaux J, Jamison JM, Neal DR, Summers JL, Cell Death By Autoschizis In TRAMP Prostate Carcinoma Cells As A Result Of Treatment By Ascorbate: Menadione Combination. Ultrastruct Pathol. 2005 May-Aug 29(3-4):221-35.

Jamison, J, Gilloteaux, J, Tsai, CC, Taper, H, Puc Calderon, P, Perlaky, L, Neal, DR, Blank, J, Getch, S, Summers, JL, Book Chapter Antioxidants: Are they Real? Aug, 2005 

Jamison JM, Gilloteaux J, Taper HS, Calderon PB, Neal DR, Blank JL, Clemens RJ and Summers JL The In Vitro and In Vivo Antitumor Activity of Vitamin C : K3 Combinations against Prostate Cancer, Progress In Prostate Cancer Research, Columbus, F (ed.), Nova Science Publishers, Inc., Hauppauge, NY. 2005.

Gilloteaux J, Jamison JM, Arnold D, Jarjoura D, Von Greuningen V and Summers JL. Autoschizis of Human Ovarian Carcinoma Cells: SEM and LM of a New Cell Death Induced by Sodium Ascorbate : Menadione Treatment. Tissue & Cell, 2004, 36, pg. 197 – 209.

Verrax, J, Cadrobbi J, Jamison JM, Marques,C, Taper HS, Habraken,Y, Piette,J, Buc Calderon P, Ascorbate Potentiates The Cytotoxicity Of Medadione Leading To An Oxidative Stress That Kills Cancer Cells By A Non-Apoptotic Caspase-3 Independent Form Of Cell Death, Apoptosis, 2004;9, pg. 223 – 233.

Julien Verrax, Marianne Delvaux, Nelson Beghein, Henryk Taper, Bernard Gallez, & Pedro Buc Calderon, Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study, Free Radical Research, June 2005; 39(6): 649–657

Jamison JM, Gilloteaux J, Nassiri MR, Venugopal M, Neal DR and Summers, JL, Induction of Cell Cycle Arrest and Autoschizis in a Human Bladder Carcinoma Cell Line by Vitamins C and K3. Biochem Pharm, 2004, 67, pg. 337-351.

Gilloteaux,J., Jamison,J., Lorimer, H., Jarjoura, D., Taper, H., Calderon, P., Neal DR and Summers ,JL, Autoschizis: a new form of cell death for human ovarian carcinoma cells following ascorbate: menadione treatment. Nuclear and DNA degradation, Tissue and Cell, 2004; 36: 197- 209.

Verrax, J.; Bollen, S.; Delvaux, M.; Taper, H.; Calderon, P. B., New Insights about the Potential Application of the Association of Vitamins C (Sodium Ascorbate) and K3 (Menadione) as Auxiliary Therapy in Cancer Treatment,

Taper, H., Jamison, J., Gilloteaux, J., Summers, J.L., and Buc Calderon, P., Inhibition of the development of metastases by dietary vitamin C:K3 combination, Life Sciences, 2004, 75, pg. 955 – 967.

Gilloteaux, J., Jamison, J., Jarjoura, D., Von Gruenigen, V., and Summers, J.L., Autoschizis of Human Ovarian Carcinoma Cells: Scanning Electron and light Microscopy of a New Cell Death Induced by Sodium Ascorbate: Menadione Treatment, Scanning, 2003, 23, pg. 137 – 149.

Gilloteaux, J., Jamison, J., Arnold, D., Taper, H., von Gruenigen, V. and Summers, J.L., Microscopic Aspects of Autoschizic Cell Death in Human Ovarian Carcinoma (2774) Cells Following Vitamin C, Vitamin K3, or Vitamin C: K3 Treatment, Microscopy and Microanalysis, 2003, 9, pg. 311 – 329.

Verrax J, Cadrobbi J, Delvaux M, Jamison JM, Gilloteaux J, Summers JL, Taper HS and Buc Calderon P. The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death.  Basis for their potential use as coadjuvants in anticancer therapy. Eur J Med Chem 2003; 38: 451-457.

Von Gruenigen, V., Jamison, J., Gilloteaux, J., Lorimer, H., Pollard, R., Gwin, C., and Summers, J.L., t, Anticancer Research, 2003, 23, pg. 3279 – 3288.

Lasalvia-Prisco, E., Cucchi, S., Vazquez,J., Lasalvia-Galante, E., Golomar, W., and Gordon, W., Serum Markers Variation Consistent with Autoschizis Induced by Ascorbic Acid-Menadione in Patients with Prostate Cancer, Medical Oncology, 2003, 20(1), pg. 1-8.

Buc Calderon, P., Cadrobbi, J., Marques, C., Hong-Ngoc, N., Jamison, J., Gilloteaux, J., Summers, J.L., and Taper, H., Potential Therapeutic Application of the Association of Vitamin C and K3 in Cancer Treatment, Current Medicinal Chemistry, 2002, 9, pg. 2269 – 2285.

Jamison, J., Gilloteaux, Taper, H., Buc Calderon, B., and Summers, J.L., Autoschizis: A novel cell death, Biochem. Pharma., 2002, 63, pg. 1773 – 1783.

Zhang W, Negoro T, Satoh K, Jiang Y, Hashimoto K, Kikuchi H, Nishikawa H, Miyata T, Yamamoto Y, Nakano K, Yasumoto E, Nakayachi T, Mineno K, Satoh T, Sakagami H, Synergistic cytotoxic action of vitamin C and vitamin K3. Anticancer Res. 2001 Sep-Oct;21(5):3439-44.

Gilloteaux, J., Jamison, J., Arnold, D., Taper, H., and Summers, J.L., Ultrastructural Aspects of Autoschizis: A Novel Cancer Cell Death by the Synergistic Action of Ascorbate/Menadione on Human Bladder Carcinoma Cells, Ultrastructural Pathology, 2001, 25, pg. 183 – 191.

Jamison, J., Gilloteaux, J., Taper, H., and Summers, J.L., Evaluation of the In Vitro and In Vivo Antitumor Activities of Vitamin C and K3 Combinations against Human Prostate Cancer, J. of Nutrition, 2001, 131, pg. 1588 – 1605.

Taper, H., Jamison, J., Gilloteaux, J., Grin, C., Gordon, T., and Summers, J.L., In Vivo Reactivation of DNases in Implanted Human Prostate Tumors after Administration of Vitamin C/K3 Combination, The J. of Histochem. And Cytochem., 2001, 49(1),pg. 109 – 119.

Gilloteaux, J., Jamison, J., Arnold, D., and Summers, J.L., Autoschizis; A new form of cell death, It. J. of Anatomy and Embryology, 2001, 106, pg 79-82.

Gilloteaux, J., Jamison, J., Arnold, D., VonGreunigen, V., Hower, R., Taper, H., and Summers, J.L., Cell Death by Autoschizis for Bladder (T24) and Ovarian Carcinoma (MDAH) Cells: LM and SEM Aspects of Morphologic Changes Induced by the Synergistic Antitumor Activity of Vitamin C:Vitamin K3 Combinations, Proceedings of Scanning, 2000, pg. 119.

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Arnold, D., Gilloteaux, J., Jamison, J., and Summers, J.L., Synergistic Effects of Vitamin C: Vitamin K3 on Human Renal Adenocarcinoma Cell Line (Caki-1): Scanning Electron Microscopy, Proceedings of Scanning, 1999, pg. 109 -110.

Nassiri, M., Gilloteaux, J., Jamison, J., and Summers, J.L., Flow Cytometric Evaluation of Two Human Carcinoma Cell Lines Confirms Cell Autoschizis Potentiated by the Synergism of Vitamin C and K3, Scanning, 1999, 21 (2), pg. 108.

Jamison, J., Gilloteaux, J., Neal, D., and Summers, J.L., Characterization of the Early Events in Vitamin C and K3-Induced Death of Human Prostate Tumor Cells, Proceedings of Scanning, 1999, pg. 107 – 108.

Gilloteaux,J., Jamison, JArnold, D., Ervin, E., Eckroat, L., Docherty, J., Neal DR and Summers , JL, Cancer Cell Necrosis by Autoschizis: Synrgism of Antitumor Activity of Vitamin C: Vitamin K3 on Human Bladder Carcinoma T24 Cells, Scanning, 1998,20, pg. 564 – 575.

Taper, H., Keyeux, A., and Roberfroid, M., Potentiation of Radiotherapy by Nontoxic Pretreatment with Combined Vitamin C and K3 in Mice Bearing Solid Transplantable Tumor, Anticancer research, 1996, 16,pg. 499 – 504.

Jamison, J., Gilloteaux, J., Venugopal, M., Koch, J., Sowick, C., Shah, R., and Summers, J.L., Flow cytometric and ultrastructural aspects of the synergistic antitumor activity of Vitamin C –vitamin K3 combinations against human prostatic carcinoma cells, Tissue and Cell, 1996, 28(6), pg. 687 – 701.

Venugopal,M., Jamison,J., Gilloteaux,J., , Koch, J., Summers,M., Hoke,J., Giammar, D. Sowick, C., and. Summers, J.L., Synergistic antitumour activity of vitamins C and K3 against human urologic tumors, Life Sciences, 1996, 59(17)pg. 1389 – 1400

Venugopal, M., Jamison, J., Gilloteaux,J., Koch, J., Summers, M., Hoke,J., Sowick, C., and. Summers,J.L., Synergistic antitumour activity of vitamins C and K3 against human prostate carcinoma cell lines, Cell Biology International, 1996, 20(12) pg. 787 – 797.

Gilloteaux, J., Jamison, J., Venugopal, M., Giammar, D., and Summers, J.L., Scanning electron microscopy and transmission electron microscopy aspects of synergistic antitumor activity of Vitamin C – Vitamin K3 Combination against human prostatic carcinoma cells, Scanning Microscopy, 1995, 9(1), pg. 159-173.

DeLoecker, W., Janssens, J., Bonte, J., and Taper, H., I. Effects of Sodium Ascorbate (Vitamin C) and 2-Methyl-1,4-napthoquinone (Vitamin K3) Treatment on Human Tumor Cell Growth in Vitro. II. Syngerism with Combined Chemotheraphy Action, Anticacer Research, 1993, 13, pg. 103 – 106.

Taper, H., and Roberfroid, M., Non-Toxic Sensitization of Cancer Chemotherapy by Combined Vitamin C and K3 Pretreatment in a Mouse Tumor resistant to Oncovin, Anticancer Research, 1992, 12, pg. 1651 – 1654.

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Noto, V., Taper, H., Yi_Hua, J., Janssens, J., Bonte, J., and DeLoecker, W., Effects of Sodium Ascorbate (Vitamin C) and 2-Methyl-1,4-Napthoquinone (Vitamin K3) Treatment on Human Tumor Cell Growth in Vitro I. Synergism of Combined Vitamin C and K3 Action, Cancer, 1989, 63, pg. 901 – 906.

Taper, H., DeGerlarche, J., Lans, M., and Roberfroid, W., Non-Toxic Potentiation of Cancer Chemotherapy by Combined C and K3 Vitamin Pretreatment, Int. J. of Cancer, 1987, 40, pg. 575 – 579.

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